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Antidote for paracetamol poisoning9/28/2023 ![]() ![]() Taking more than this amount risks permanent and even fatal liver damage. An adult body can produce enough glutathione to safely clear 4 grams of paracetamol every 24 hours which is why it is the recommended dose. If the glutathione runs out, then the toxic substances build up and damage liver cells. A substance called glutathione is needed to neutralise the toxic break down components of paracetamol. The liver can only cope with so much paracetamol at one time. Paracetamol is mainly cleared from the body by the liver. If you have taken more than the recommended dose you should attend Accident and Emergency to be assessed as soon as possible. Taking a few extra tablets each day over a number of days could push you into harmful toxic levels and result in liver damage and possibly death. Some overdoses are taken intentionally as an act of self-harm but many are accidental. You should not take more than this recommended dose. At least four to six hours should be left between doses. Each tablet of paracetamol contains 500 milligrams so this equates to two tablets four times a day with a maximum daily dose of 4 grams or eight tablets. The recommended adult dose of paracetamol is 1 gram, four times a day. ![]()
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